IISER Pune
INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IISER) PUNE
where tomorrow’s science begins today
An Autonomous Institution, Ministry of Human Resource Development, Govt. of India
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Seminars and Colloquia

Physics

A mechanistic model of the cellular resource allocation strategy in bacteria 
 
Fri, Jan 10, 2020,   12:00 PM at Seminar Hall 31, 2nd Floor, Main Building

Dr. Anjan Roy
ICTP, Trieste

Abstract: Bacterial growth requires protein synthesis. It is carried out proteins. However, being made up of protein sub-units themselves the proteins converting environmental nutrients into amino acids, but also interesting trade-off of how much of its ribosomes should it allocate to
producing more ribosomes as opposed to producing other proteins, so as to 
We present a simple, mechanistic model which demonstrates this trade-off,the growth rate of the cell. Moreover, bacteria must dynamically adapt uses a simple feedback mechanism to achieve this, by dynamically driving
this allocation parameter towards the optimal value for different
environments. The resultant model is consequently capable of explaining antibiotic and other such perturbations under one unified framework.

 

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