IISER Pune
INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IISER) PUNE
where tomorrow’s science begins today
An Autonomous Institution, Ministry of Human Resource Development, Govt. of India
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Seminars and Colloquia

Physics

Physical interactions and order in cells 
 
Wed, Sep 06, 2017,   04:00 PM at Physics Seminar Room 31, 2nd Floor, Main Building

Dr. Kinjal Dasbiswas
James Franck Institute, University of Chicago

There is mounting recent evidence that physical interactions help to organize biological cells. In particular, many cells actively generate forces through molecular motors that enable them to interact mechanically through soft substrates and achieve ordered states.  To take an example, we look at how spatial order in heart muscle cells and their temporal beating are correlated. This can be understood through the notion of an order parameter arising out of the competition of an elasticity-driven force and noise inherent in biology.  Complementary to this elastic picture, other forms of order can arise in a more liquid-like context in biomaterials.  This is a recurring theme in biology because cells have both solid- and fluid-like properties.  Mechanical interactions, which are faster and longer ranged than the diffusion of chemical signals, may also underlie pattern formation processes inherent in biology. We sketch how such a mechanochemical collaboration can theoretically explain the size scaling during tissue development that ensures proportionate organisms.  I will conclude by indicating how notions of topologically protected edge states may enable robust localized flows of information and matter in biology. 

 

 

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