Post-publication review and PLOS’ experiment with the Synthetic Biology Collection

October28

An inducible luxI system (iptg) to produce the AHL above a threshold Pt. Kadam et al. (2016)

The iGEM 2015 synthetic biology contest was an important one for us. It marked our first attempt at putting together a project from IISER Pune. But beyond the novelty for us, many things were different this time around (#igem2015). First off, no preliminary or elimination rounds.

Secondly, we (yes, some self-backpatting here) organized an India Meetup in the run-up to the Jamboree. And third, and interestingly, the journal PLOS One (Public Library of Science) decided to use this as an opportunity to launch the PLOS iGEM collection, as a sort of meta-list, connected to iGEM. They decided to also go the radical way- with post-publication review. Time will tell how this latter experiment works out. And naturally our team’s efforts are there. With a lot of hard work put in by Snehal Kadam well after the contest and some griding-the-article together by mining long-forgotten (1 year ago!) protocol books, and some frantic emailing and interviewing, we managed to pull it off. You can read it here “Mycobacterium Revelio: Characterizing and Modeling Genetic Circuit Components towards a Bacterial Detection Tool”. The first 10 authors are BS-MS undergraduate students. Manasi and Neha are PhD students.

iGEM

July26

In 2015 we hosted an iGEM team form IISER Pune. The theme was Mycobacterium revelio- in the spirit of Harry and his revleaing charm. Mycobacterium tuberculosis is prevalent worldwide, but India tops the charts for prevalance. Our project aimed to produce a novel diagnistic tool for low cost and rapid detection.

L to R: Snehal, Ira, Prachiti, Prashant, Yash and Siddhesh.

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