Synthetic morphogenesis at EMBL Heidelberg

March30

The use of synthetic biology in engineering biological systems has been rapidly expanding. the conference at EMBL Heidelberg from 17-20 March 2019 on “Synthetic Morphogenesis: From Gene Circuits to Tissue Architecture” highlighted this in the context of understanding growth and developmental morphogenesis. It brought together an unusual combination of researchers ranging from:

  • in vitro reconstitution of cytoskeletal networks
  • giant unilammelar vesicles (GUVs) for encapsulating proteins: towards synthetic cells
  • rebuilding gradients of morphogens by engineering cells
  • organoid models of tissue morphogenesis
  • engineering blastulas and developing embryos predictively modify developmental outcomes

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