Glycogen synthase kinase-3 beta

In vitro report. GSK3beta is shown to phosphorylate specifically the H1.5 variant of H1 during metaphase and this phosphorylation mark is erased after telophase (PMID: 19136008).

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Glycogen synthase kinase-3 beta (GSK-3 beta) infosheet
UniprotKB AccessionP49841
Alternative Name(s)
Writer for PTM/s H1T10ph
EC number
No. of coding genesGlycogen synthase kinase-3 beta is coded by following 1 non-allelic gene/s
Gene nameglycogen synthase kinase 3 beta
Gene symbolGSK3B
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s
Chromosomal location3q13.3
RefSeq mRNANM_001146156.1NM_002093.3
RefSeq ProteinNP_001139628.1NP_002084.2
Disease associationsNo disease associations known for Glycogen synthase kinase-3 beta

Serine/threonine/tyrosine kinases Cyclin-dependent kinase 17, Cyclin-dependent kinase 3, Cyclin-dependent kinase 5, Death-associated protein kinase 3, DNA-dependent protein kinase catalytic subunit, Glycogen synthase kinase-3 beta, Inhibitor of nuclear factor kappa-B kinase subunit alpha, LIM domain kinase 2, Microtubule-associated serine/threonine-protein kinase-like, Mitogen-activated protein kinase kinase kinase 8, Mitogen-activated protein kinase kinase kinase MLT, Mitotic checkpoint serine/threonine-protein kinase BUB1, Protein kinase C beta type, Protein kinase C delta type, Ribosomal protein S6 kinase alpha-4, Ribosomal protein S6 kinase alpha-5, Serine-protein kinase ATM, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 4, Serine/threonine-protein kinase ATR, Serine/threonine-protein kinase haspin, Serine/threonine-protein kinase N1, Serine/threonine-protein kinase Nek6, Serine/threonine-protein kinase Nek9, Serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase tousled-like 1, Tyrosine-protein kinase BAZ1B, Tyrosine-protein kinase JAK2