L S Shashidhara
Professor and Coordinator, Biology
Indian Institute of Science Education and Research
Dr. Homi Bhabha Road
Pune - 411008. (Maharashtra)
previous work experience
B.Sc. and M.Sc., University of Agricultural Sciences, Dharwad, India
1987-88 Teaching Associate, University of Agricultural Sciences,
1988-91 Ph.D., Cambridge, UK
1991-93 PDF, Cambridge, UK
1993-95 Visiting Fellow, NCBS, Bangalore
Scientist (Group Leader), CCMB, Hyderabad
2007- Professor (Biology), IISER, Pune
- JC Bose National Fellowship
- SS Bhatnagar Prize (Biological
- Fellow, Indian National Science
- Fellow, Indian Academy of
- Fellow, National Academy of
- Honorary Faculty Member,
- DAE-SRC Outstanding Research
- CSIR Technology award in the
area of Biological Sciences
Genetics and Developmental
of appendage forms
of homeotic selector (Hox) gene function
Recent Publications(for full list visit PubMed)
- Agrawal, P., Habib, F.,
Yelagandula, R. and Shashidhara, L.S. (2011). Genome-level
identification of targets of Hox protein Ultrabithorax in Drosophila:
novel mechanisms for target selection. Scientific Reports 1, DOI:
- Ghose, A. and Shashidhara, L.S.
(2011). Cyclin beyond the cell cycle: new partners at the synapse.
Developmental Cell. 21, 601-12.
- Tripura, CB, Prafulla
Chandrika, NN, Susmita, VNL, Noselli, S. and Shashidhara, LS (2011). A
role for Odd-skipped in regulating JNK activity in the wing disc
peripodial membrane during adult morphogenesis in Drosophila.
International Journal of Developmental Biology 55, 583-90.
- Usha, N. and Shashidhara, L.S.
(2010). Interaction between Ataxin-2 Binding Protein 1 and
Cubitus-interruptus during wing development in Drosophila.
Developmental Biology 341, 389–399.
- Gurudatta, B.V., Shashidhara,
L.S. and Parnaik., V.K. (2010). Lamin C and chromatin organization in
Drosophila. J Genetics 89, 37-49.
- Berger, C., Ramakrishnan, K.,
Myneni, S., Renner, S., Shashidhara, L.S. and Technau, G.M. (2010).
Cell cycle independent role of Cyclin E during neural cell fate
specification in Drosophila is mediated by its regulation of Prospero
function. Developmental Biology 337, 415–424.
- Ramakrishnan, K., Berger, C.,
Myneni, S., Technau, G.M. and Shashidhara, L.S. (2010). Abdominal-A
mediated repression of Cyclin E expression during cell-fate
specification in the Drosophila central nervous system. Mechanisms of
Development 127, 137-145.
- Vyas, N., Goswami,
D., Manonmani, A., Sharma, P., Ranganath, H.A., VijayRaghavan,
K., Shashidhara, L.S., Sowdhamini,
R. and Mayor, S. Nanoscale organization of Hh is
essential for long range signaling. Cell 133, 1214-1227. (2008).
- Gupta, R.K., Tripathi, R.,
Naidu, B.J., Srinivas, U.K. and Shashidhara,
L.S. Cell cycle regulation by the pro-apoptotic gene Scotin. Cell
Cycle 7, 2401-2408 (2008).
- Ramesh Rao, P., Makhijani, K.
and Shashidhara, L. S.Human APC sequesters beta-catenin even in the
absence of GSK-3beta in a Drosophila model. Oncogene 27, 2488-2493.
- Aritakula, A., Ramaswamy, A.
and Shashidhara, L.S.Actin Cytoskeleton as a Putative Target of the
Neem Limonoid Azadirachtin A. Insect Biochemistry and Molecular Biology
37, 627-634. (2007).
- Makhijani, K., Chilukuri, K.,
Tamarisa, S. and Shashidhara, L.S.Modulation of Decapentaplegic
gradient during haltere specification in Drosophila. Developmental
Biology 302, 243-255. (2007).
- Pallavi, S.K., Kannan, R. and
Shashidhara, L.S.Negative regulation of Egfr/Ras pathway by
Ultrabithorax during haltere development in Drosophila. Developmental
Biology 296, 340-352. (2006).
- Mohit, P., Makhijani, K.,
Madhavi, M.B., Bharathi, V., Lal, A., Sirdesai, G., Reddy, V.R.,
Ramesh, P., Kannan, R., Dhawan, J. and Shashidhara, L.S. Modulation of
AP and DV signalling pathways by the Homeotic gene Ultrabithorax during
haltere development in Drosophila. Developmental Biology 291, 356-367.
- Pallavi, S.K. and Shashidhara,
L.S.Signaling interactions between squamous and columnar epithelia of
Drosophila wing disc. J Cell Science 118, 3363-3370. (2005).
C., Pallavi, S.K., Mohit, P., Shashidhara L.S. and Technau, G.M.A
critical role for Cyclin E in cell fate determination in the central
nervous system of Drosophila. Nature Cell Biology 7, 56-62. (2005).