About Us Faculty On Campus Administration Events News & Views Careers
   You are here -> Home -> Faculty -> N.K.Subhedar
 

N K Subhedar
Visiting Faculty, Biology
E-mail: subhedar@iiserpune.ac.in

Website:

Educational and previous work experience

1963-66 B.Sc. Nagpur University, Nagpur, India

1966-68 M.Sc. University of Pune, Pune, India

1968-73 Ph.D.Nagpur University, Nagpur, India

1972-86 Lecturer, Department of Pharmaceutical Sciences, Nagpur University, Nagpur, India

1980-81 PDF, University of Hong Kong, Hong Kong

1986-1997 Reader, Department of Pharmaceutical Sciences, Nagpur University, Nagpur, India

1995-96 PDF, Whitney Laboratory, University of Florida, USA

2000-01 PDF, Sanders Brown Center on Aging, College of Medicine, University of Kentucky, USA

1997-2008 - Professor of Pharmacology, Department of Pharmaceutical Sciences, Nagpur University, Nagpur, India

Awards and Honors:

1. Bursary Award, The Royal Society, London
2. Fellow, Maharashtra Academy of Sciences
3. Fellow, National Academy of Sciences, India
4. President, The Indian Society for Comparative Endocrinology
5. President, India Sub-continental Branch of the International Neuropeptide Society
6. Co-chairman, DST-SERC School in Neurosciences
7. Chairman, DST-SERC School on clock, rhythm and behaviour

Research interests (specialization: Neurosciences, neuropeptides and behavior)

1. Neuropeptides and processing of information in brain
2. Neuroendocrine regulation of pituitary and reproduction in teleosts
3. Neuropharmacology of addiction and drug abuse

Recent Publications

  1. Singru, P.S. Mazumdar, M., Barsagade, V., Lechan R.M., Thim, L., Clausen, J.S., Subhedar, N.K. (2008). Association of cocaine-and amphetamine-regulated transcript and neuropeptide Y in the forebrain and pituitary of the catfish, Clarias batrachus: A double immunofluorescent labeling study. J. Chem Neuroanat. (in press: doi:10.1016/j.jchemneu.2008.07.002).

  2. Kokare DM, Singru PS, Dandekar MP, Chopde CT, Subhedar NK. (2008) Involvement of alpha-melanocyte stimulating hormone (alpha-MSH) in differential ethanol exposure and withdrawal related depression in rat: neuroanatomical-behavioral correlates.Brain Res. 1216:53-67.

  3. Dandekar, M.P., Singru, P.S., Kokare, D.M., Lechan R.M., Thim, L., Clausen, J.T., Subhedar, N.K. (2008). Importance of cocaine-and amphetamine-regulated transcript peptide (CARTp) in the hypothalamus and amygdala in anxiogenic responses induced by ethanol withdrawal. Neuropsychopharmacology. 33:1127-1136.

  4. Kalange, A.S., Kokare, D.M., Singru, P.S., Chopde, C.T., Subhedar. N (2007) Central administration of selective melanocortin-4 receptor antagonist HS014 prevented morphine tolerance and withdrawal hyperalgesia. Brain Research 1181:10-20.

  5. Ugale RR, Sharma AN, Kokare DM, Hirani K, Subhedar NK, Chopde CT.(2007) Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats.Brain Res. 1184:193-201.

  6. Mazumdar M, Sakharkar AJ, Singru PS, Subhedar N. (2007) Reproduction phase-related variations in neuropeptide Y immunoreactivity in the olfactory system, forebrain and pituitary of the female catfish, Clarias batrachus (Linn.). Journal of Comparative Neurology 504:450-469.

  7. Singru, P.S., Mazumdar, M., Sakharkar, A. M., Lechan, R. M., Thim, L., Clausen T.J. Subhedar N.K. (2007) Immunohistochemical localization of cocaine- and amphetamine-regulated transcript peptide in the brain of the catfish, Clarias batrachus (Linn.). Journal of Comparative Neurology 502:215-235.

  8. Goyal, S.N., Kokare, D.M., Chopde, C.T. Subhedar, N.K. (2006). alpha-Melanocyte stimulating hormone antagonizes antidepressant-like effect of neuropeptide Y in Porsolt’s test. Pharmacology, Biochemistry and Behavior 85:369-377.

  9. Getchell, M.L., Li, H., Vaishnav, R.A., Borders, A.S., Witta, J., Subhedar, N., de Villiers, W., Stromberg, A.J., Getchell, T.V. (2006). Temporal gene expression profiles of target-ablated olfactory epithelium in mice with disrupted expression on scavenger receptor An impact on macrophages. Physiol. Genomics 27:245-63.

  10. Kokare, D.M., Chopde, C.T., and Subhedar, N.K. (2006) Participation of alpha-melanocyte stimulating hormone in ethanol-induced anxiolysis and withdrawal anxiety in rats. Neuropharmacology 51:536-545.

  11. Mazumdar, M., Lal, B., Sakharkar, A.J. Deshmukh, M., Singru, P., and Subhedar, N. (2006) Involvement of neuropeptide Y Y1 receptors in the regulation of LH and GH cells in the pituitary of the catfish, Clarias batrachus: an immunocytochemical study. Gen. Comp. Endocrinol. 149:190-196.

  12. Subhedar N. (2006). An update on the neuropeptide Y in the brain of vertebrates. Special Asok Ghosh Commemoration Volume; Proc. Zool. Soc. Calcutta 59:71-86.

  13. Sakharkar, A.J., Singru, P.S., Mazumdar, M. and Subhedar, N. (2006). Reproduction phase-related expression of beta-endorphin-like immunoreactivity in the nucleus lateralis tuberis of the female Indian major carp Cirrhinus mrigala: correlation with the luteinising hormone cells-ovary axis. J. Neuroendocrinology 18:319–329

  14. Kokare, D.M. Patole, A.M. Carta, A., Chopde, C.T. Subhedar, N. (2006) GABAA receptors mediate orexin-A induced stimulation of food intake. Neuropharmacology 50:16-24

  15. Mazumdar, M., Singru, P., Sakharkar, A.J. Deshmukh, M., Subhedar, N. (2005). Glucagon-like peptide-1 (GLP-1) immunoreactivity in the forebrain and pituitary of the teleost, Clarias batrachus (Linn.) Fish Physiol. Biochem. 31:173-176.

  16. Subhedar, N. Gaikwad, A., Biju, K.C. Saha, S. (2005) Role of neuropeptide Y (NPY) in the regulation of reproduction: study based on catfish model. Fish Physiol. Biochem. 31:167-172.

  17. Sakharkar, A.J., Singru, P.S., Sarkar, K. and Subhedar, N. (2005). Neuropeptide Y in the forebrain of the adult male cichlid fish Oreochromis mossambicus: distribution, effects of castration and testosterone replacement. Journal of Comparative Neurology 489:148–165

  18. Gaikwad, A, Biju, K.C., Muthal, P L. Saha S. and Subhedar, N. (2005) Role of neuropeptide Y in the regulation of GnRH system in the forebrain of Clarias batrachus (Linn.): Immunocytochemistry and HPLC-electrospray ionization mass spectrometric analysis. Neuroscience 133:267-279.

  19. Kokare, D.M., Dandekar, M. P., Chopde, C.T. and Subhedar, N. (2005) Interaction between neuropeptide Y and alpha-melanocyte stimulating hormone in amygdala regulates anxiety in rats. Brain Research 1043:107-114.

  20. Biju, K.C., Gaikwad, A, Sarkar, S., Schreibman, M.P. and Subhedar, N. (2005) Ontogeny of GnRH-like immunoreactive neuronal systems in the forebrain of the Indian major carp, Cirrhinus mrigala. Gen. Comp. Endocrinol. 141/2:161-171.

  21. Kwong, K., Vaishnavi R.A., Liu, Y., Subhedar, N., Stromberg, A.J., Getchell, M.L. and Getchell, T.V. (2004) Target ablation induced regulation of macrophage recruitment into the olfactory epithelium of MIP-1?-/- mice and restoration of function by exogenous MIP-1? Physiol. Genomics 20:73-86.

  22. Gaikwad, A., Biju. K. C., Saha, S.G. and Subhedar N. (2004) Neuropeptide Y in the olfactory system, forebrain and pituitary of the teleost, Clarias batrachus. J. Chem. Neuroanat. 27:55-70